Abstract

Muki amaderaspatana is a wild functional food plant belonging to the family cucurbitaceae, mostly prevalent in South India.It is distributed throughout the tropical and sub tropical region; Also known as, Musumusukkai in Tamil. It has been used in Indian traditional medicine for centuries. In traditional systems of medicine, various plant parts such as roots, leaves have been used to alleviate a number of human and livestock ailments. The purpose of the present review is, understanding of its medicinal properties and to reveal the possible effect of this plant in the development of therapeutically active herbal drugs. In this review results shows as; The leaf has the great potency to act as natural antioxidant because of the presence of Phenolic compounds and flavanoids and other pharmacological activites reported by various in vitro and in vivo studies such as; Anti-hypertensive, Anti-oxidant, Hepatoprotective, Immunomodulatory, Antihyperglycaemic, Antihyperlipidemic, Antiplatelet aggregation, Antimicrobial, Antiulcer, Anxiolytic, Local anaesthetic etc. The fresh plant posses the broad spectrum antimicrobial activity against various bacterial strains including Bacillus cereus, Enterococcus faecalis, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Klebsiellapneumoniae, Pseudomonas aeruginosa and Salmonella typhimurium and also possess prominent activities against the fungal strains such as Candida tropicalisandTrichophytonrubrum. Finally concluded that Mukiamaderaspatana whole plant possesses a myriad health care potentials therefore, strongly recommended to include this plant as a dietary supplement same as mentioned in ancient Traditional Siddha systems of medicine respectively.