Abstract

PhyllanthusEmblica(Amla) are widely used in the Indian system of medicine and believed to increase defense against diseases. This drug is available to manage  diabetics, liver diseases, heart disease, cancer,ulcer,haemorrhoids, anemia and various other diseases.( YaduNandanDey and Ajoy Kumar Ghosh,. 2010).Siddha formulation of Nelli Kudineer (PhyllanthusEmblica)was investigated for its antihelmintic activity against Pheretimaposthuma and Tubifextubifex. The extract with the concentrations of 25, 50 and 100 mg/ml were tested in the bioassay, which involved determination of time of paralysis and time of death of the worms. The extract exhibited significant antihelmintic activity at highest concentration of 100 mg/ml. Piperazine citrate (10 mg/ml) was included as standard reference and distilled water as control. The extracts were found not only to paralyze (Vermifuge) but also to kill the earthworms (Vermicidal).