Abstract

Hyperlipidemia is one among the Non communicable disease with its incidence on the raise across the globe. High-energy, high-fat, and high-saturated fatty acid diet, which can promote the synthesis of cholesterol, is the most common risk factor of hyperlipidemia, especially hypercholesterolemia. Hypercholesterolemia, a significant cardiovascular risk factor, is one of the major oxidative stresses that generate excess of highly reactive free radicals. This exacerbates the development and progression of atherogenesis induced hypercholesterolemia with a risk of increased LDLc or more accurately LDLc/ HDLc ratio. The atherogenic index can be decreased by reduction in LDLc and increment in HDLc. Further health risks due to hypercholestremia could be kept in check with drugs having the property to reduce the cholesterol level and to scavenge the free radicals. Siddha system of medicine uses a wide range of herbs with the similar potency based on taste. This paper is a collection of some herbs like fenugreek, garlic, onion, turmeric, cumin seeds that are commonly used in day to day life, as medicines in treating ailments, as kayakalpam and to explore their lipid lowering activity that are commonly used in Siddha system of medicine on scientific background.