Abstract

Vitiligo is an acquired depigmenting disorder of the skin resulting from loss of functional melanocytes. It often affects adult and children.It can have a variable age of onset, but many studies have reported that around 50% of the patients have an onset before the age of 18 years and a quarter before the age of 8 years. However, the social impact on children is that it leads to psychological distress and affects self-esteem of the children. In classical siddha literature  vitiligo is named as venpadai which is one type of kuttam. Among 18 varieties of kuttam, it is noted as venkuttam or swethakuttam in yugichinthamani. Various causes were given in literature includes constant irritation made in the skin by an object, ductless glands, malnutrition, genetic factors, secondary to syphilis, leprosy and some of the microorganisms. In siddha literature agathiyar vaithiya pillai tamil, Ilaguseena chooranam is indicated for venkuttam which is purely a herbal medicine that is safe and effective. The research and analysis in this siddha medicineIlagu seena chooranam will bring out the effectiveness of drug scientifically. The preliminary study and qualitative analysis will paved a way for further clinical studies in this trial drug. The biochemical analysis of the trial drug indicates the presence of Sulphate, Starch, Ferrous Iron, Unsaturated Compound,Reducing sugar, Amino Acid revealed the enhancement of therapeutic action in vitiligo