Abstract

Munnailai kudineer(MK) is the Siddha formulation used in the treatment of vatha diseases and in pain magement. The aim of this present study is to evaluate the acute and  sub acute toxicity of Munnaiilai kudineer. Toxicity of Munnaiilai kudineer is carried out as per the guidelines Organization of Economic Co-operation and Development (OECD) -423 guidelines. The result of toxicity study shows that there was no significant change in animal behavior due to the absence of toxicity.   The animals treated with MK showed normal growth pattern and body weight compared with control rats treated with normal saline. The overall results suggest that Munnaiilaikudineerare non-toxic to the haaematopoietic and leucopoietic system.