Biochemical analysis of Siddha Kalpa Medicine ‘’Vilam Pazha Karpam’’

Joshi.I¹ , Mohammed Fizel.M 2, Poongodi Kanthimathi.A.S3

1PG Scholar, Department of siddhar yoga Maruthuvam, ² PG Scholar, Department of pura Maruthuvam, 3 Head of the Department , Department of Sirappu Maruthuvam, Government Siddha Medical College & Hospital, Palayamkottai, Tirunelveli

ABSTRACT

Siddha system is a traditional system of medicine practicing in southern part of the India. Kaya karpam means (kaayam-body, karpam-able competent) to make our body competent and youthful. The karpam or Kalpa medicines are those which prevent graying wrinkling of skin, aging, senile changes and other disease for promoting longevity with complete freedom from illness. Kaya karpam provides both mental and physical wellness. Vilam pazha karpam from theraiyar kapiyam is indicated for Pitha vatham. It is correlated to Hypertension which is also known as high blood pressure. High blood pressure is classified as primary hypertension and secondary hypertension. 95% of cases are primary hypertension. As high blood pressure due to non specific life style and genetic factor.

The aim of the study was to evaluate the biochemical analysis of the siddha karpam ‘vilam pazha karpam and it indicate the presence of calcium, sulphate, chloride, ferrous iron, unsaturated compound, reducing sugar which revealed the enhancement of therapeutic action in hypertension.

keywords: high blood pressure, primary hypertension, kaya karpam, biochemical analysis, Limonia acidissima

INTRODUCTION:

Hypertension is the most common cardiovascular disease and is a major public health issue in developed as well as developing countries. Although it is common and readily detectable, it can often lead to lethal complications, if left untreated. Primary Hypertension is the most common type of hypertension, affecting 95% of hypertensive patients. It has no identifiable cause. It is the primary cause of stroke, coronary artery disease and sudden cardiac death. Approximately 20% of the world’s adults are estimated to have hypertension, when hypertension is defined as Blood pressure in excess of 140/90 mm Hg. The prevalence dramatically increases in patients older than 60 year. Persons of primary hypertension are having Giddiness, Dizziness, Palpitations, Dyspnoea, Insomnia and Fatigue.

Vilam pazham (limonia acidissima) has common names in English are wood apple and elephant apple. The fruit contains fruit acids, vitamins and minerals. The fruit is also astringent and cardiac tonic.

MATERIALS & METHODS:

Table 1. Ingredients of Vilam pazha karpam

Collection, Identification and Authentication of the Drug:

The required raw drugs were purchased from a well reputed country shop and it was authenticated from Medical Botanist of Government Siddha Medical College, Palayamkottai.

Purification of the Drug:

All the ingredients of this herbal formulation were purified according to the proper produce methods described in Siddha Classical Literature.

Preparation of the drug:

The purified raw drugs are coarsely powdered and mixed in of each equal quantity. The decoction is made out from the above mixture as per the method available in Siddha literatures.

Biochemical analysis:

Screening the drug Vilam pazha karpam to identify the Biochemical properties present in the ingredient.

Chemicals and drugs:

An the chemicals used in this study were of analytical grade obtain from Department of Biochemistry, Government Siddha Medical College & Hospital, Palayamkottai.

Methodology:

5 grams of the drug was weighed accurately and placed in a 250ml clean beaker. Then 50ml of distilled water added to it and dissolved well. Then it was boiled well for about 10 minutes. It was cooled and filtered in a 100ml volumetric flask and then it is made upto 100ml with distilled water. This fluid was taken for analysis.

Table 2. Qualitative Analysis of Vilam Pazha karpam

RESULTS AND DISCUSSION:

The Bio chemical analysis of the trial drug Vilam pazha karpam was tabulated above in table 2. The trial drug , Vilam pazha karpam it contains, Sulphate, Chloride, Starch, Calcium, Ferrous ion, Unsaturated compound, Amino acid,Ferrous iron, Reducing sugar. The mode of action of the trial drug Vilam pazha karpam which brings about the Bone Mineralization, osteoblastic and osteoclastic activity in body which may be due to the presence of Sulphate, Amino acid, Ferrous Iron in it.

Conclusion:

Vilam pazha karpam is a (1)Siddha medicine taken(2) from a Siddha literature used for the treatment of hypertension (vadha pitham). The drug is screened(3) for its bio chemic(4)al properties. Further, comprehensive pharmacological analysis are needed to evaluate its potency and the drug has its own potency to undergo further research.

ACKNOWLEDGEMENT

The author wish to acknowledge our hearty thanks to Dr.A.S.Poongodi Kanthimathi Head of the Department, Department of Sirappu Maruthuvam , Department of Biochemistry , Government Siddha Medical College & Hospital, Palayamkottai and thanks to my department faculties.

References:

1. M S. Noinaadal Noimudhal Naadal Thirattu part-II. 3rd ed. Chennai: Indian medicine and homeopathy department, Tamil Nadu State Government, Arumbakkam; 2003. 262 p.

2. Murugesa Muthaliar. Siddha Materia Medica (Vegetable section),. 1st ed. Vol. 1. Chennai: Department of Indian Medicine and Homeopathy; 1988. 345 p.

3. K. N. Kuppusamy Muthaliar. Siddhar Pothu Maruthuvam. 2nd ed. Chennai: Department of Indian Medicine and Homeopathy; 2012. 672 p.

4. Ministry of AYUSH. The Siddha Pharmacopoeia of India [Internet]. 2nd ed. Vol. 1. New Delhi: Central Council for Research in Ayurveda and Siddha CCRAS; Available from: http://nischennai.org/uploaded/pdf/THE%20SIDDHA%20PHARMACOPOEIA%20OF%20INDIA.pdf