Preliminary Chemical analysis of Kirumi ennai-polyherbo-mineral formulae in Siddha

Esakki Muthu K^1*, Bibina I¹, Soundararajan DK ²

^1* PG Scholars,Department of Kuzhandhai Maruthuvam,Government Siddha Medical College and Hospital,Palayamkottai.

² Professor andHOD, Department of Kuzhandhai Maruthuvam,Government Siddha Medical College and Hospital,Palayamkottai.

ABSTRACT

Siddha system is one of the oldest systems of medicine in India.The term ‘Siddha’ means achievements and ‘Siddhars’ were saintly persons who achieved results in medicine.The knowledge of plants and minerals were of very high order and they were fully acquainted with almost all the branches of science.The active phytochemical constituents of individual plants are inadequate and do not give desirable therapeutic effects ,when polyherbal and herbo-mineral formulations combining the multiple herbs in peticulous ratio,it will give an enhanced therapeutic effect and decrease the toxicity.Kirumi ennai is a polyherbo-mineral formula in siddha is used to treat Kudal kirumikal (Worm infestation) in children. This paper describes the qualitative analysis of Kirumi ennai .The phytochemical analysis of Kirumi ennaiindicates the presence of calcium,sulphate,chloride,starch,tannic acid,unsaturated compound,reducing sugar and amino acid revealed the enhancement of therapeutic action in Kudal kirumikal (Worm infestation).

Key words:

Kirumi ennai, Kudal kirumikal (Worm infestation), Phytochemical analysis, Siddha system.

INTRODUCTION

Siddhars were spiritual masters who possessed the ashta (eight) siddhis or unique powers. Agastyar or Agasthya ,is believed to be the founding father of Siddha medicine.The Siddha system is largely therapeutic in nature. In siddha, the Paediatrics is called as, Kuzhanthai Maruthuvam and Pillaipini Maruthuvam. “The healthy children are the backbone of a healthy society”. But they were suffered from lot of viral and bacterial infection. Kudal kirumikal (worm infestation)one of them which is causedby contact with an infected surface such as soil containing eggs or germs at a playground or touching pets infected with worms.Consuming infected food with worms,Improper hygieneand Improper hand washing .Some common symptoms of Kudal kirumikal (worm infestation) are irritability,weight loss,stomach ache,bed wetting,blood in stools.

Tape worm infection -Jaundice, nausea,vomiting,loss of appetite,eating too frequentlyand sometimes even malnutrition.

Round worm infection -Diarrhoea,passing worms with stools,dry cough,fever.

Pinworm infection - Itching around the anus,trouble sleeping due to itching,painful urination.

Hookworm infection -Wheezing, coughing, fatigue, anaemia.

Worm infestations and related infections are common in children and are also easily treated. So I decide to choosen kirumi ennai-polyherbo mineral formula is taken from theSiddha text literature Pillai Pini Maruthuvam Part -I to treat Kudal kirumikal (worm infestation) in children.

METHODS AND MATERIALS

Table.1 (Ingredients of Kirumi ennai )

Collection ,Identification and Authentication of the Drug:

The required raw drugs were purchased from a well reputed country shop. The plants are collected in our native place. They were authenticated by Botanist,Department of Medicinal Botany and mineral authenticated by Department of Gunapadam,Government Siddha Medical College, Palayamkottai

Purification of the Drug:

All the ingredients of this herbal formulation were purified according to the properproduce methods described in Siddha Classical Literature.

Preparation of the drug :

Juices are extracted from the leaves of raw materials 1 to 5. Raw material 6 to 15 are pulverized and seieved separately.This powder is then made into a pasteby missing with small quantity of the extracted juices. This is then mixed with castor oil in a vessel and is heated.

Once the karkam of oil attains “MEZHUGU” consistency, the heating should be stopped and oil is filtered and stored in glass container.

Phytochemical analysis:

Screening the drug Kirumi ennai to to identify the Phytochemical properties present in the ingredients

Chemicals and drugs:

All the chemicals used in this study were of analytical grade obtain from Department of Biochemistry, Government Siddha Medical College, Palayamkottai.

Methodology:

5 grams of the drug was weighed accurately and placed in a 250ml clean beaker. Then 50ml of distilled water added to it and dissolved well. Then it was boiled well for about 10 minutes. It was cooled and filtered in a 100ml volumetric flask and then it is made upto 100ml with distilled water. This fluid was taken for analysis.

Table .2 QUALITATIVE ANALYSIS OF KIRUMI ENNAI

RESULTS AND DISCUSSION

The Phytochemical analysis of the trial drug Kirumi ennai was tabulated above in table 2.

The trial drug Kirumi ennai contains.

• Calcium
• Sulphate
• Chloride
• Starch
• Tannic acid
• Unsaturated compound
• Reducing sugar
• Amino acid

The mode of action of the trial drug kirumi ennai is bringing about change in hypopigmented patches on face and pruritus,which may be due to the presence of sulphate,starch,tannic acid in it.

CONCLUSION:

Kirumi ennai the siddha drug taken from a Siddha literature is used in the treatment of Kudal kirumikal.The drug is screened for its Phytochemical properties.Further,comprehensive pharmacological analysis is needed to evaluate its potency and the drug has its own potency to undergo further research.

REFERENCES:

1.Dr. Sundar rajan ,Pillai pini maruthuvam,Part I- First edition

Department of Indian Medicine and Homeopathy-Chennai.

2. Ponguru sironmani, Balavaagadam,Fifth edition 2016. Department of Indian Medicine and Homeopathy-Chennai.