Qualitative chemical analysis of Siddha polyherbal drug Panchadeepakini chooranam

Karthika.Ar*¹, Karthika.S¹, Soundararajan.D.K ³

1.PG Scholar, Department of KuzhanthaiMaruthuvam

2.Head of the Department,Department of KuzhanthaiMaruthuvam

Government siddha Medical College, Palayamkottai, Tirunelveli

ABSTRACT

Diarrhoea in children is most important pathological condition in pediatrics.Because, it is second leading cause of death among children under 5 years of age. Globally, there were about 2.5 million death occur per year in every quarter of all childhood death. The causative micro organisms were bacteria ,virus and parasites. Among this Salmonella, Shigella were common. Bacillary dysentery is caused by shigella species characterized by diarrhoea along with blood and mucus.Inour classical siddha literature, Balavagadam the diseases of children are broadly classified into Agakarananoigal and Purakarananoigal. Kalichal is one among the Purakarananoigaland is divided into three types- maanthakalichal, kana kalichal and aamakalichal. Aamakalichal is a commonly occurring disease in infants and children. In pillaipinimaruthuvam, an indication for Aamakalichal is Panchadeepakinichooranam which is purely a herbal medicine.The qualitative chemical analysis of the trial drug is essential as it is helpful for further clinical studies. The biochemical analysis of the trial drug indicates the presence of calcium, sulphate,Chloride, Starch, Ferrous Iron, Unsaturated Compound, Amino Acid revealed the enhancement of therapeutic action in Aamakalichal

Keywords:

Siddha system, Aamakalichal, Panchadeepakinichooranam,Diarrhoea, Biochemical analysis.

Introduction:

Among the gastrointestinal disorders in children, diarrhoeal disorder is notable disease as it accounts for second leading cause of mortality in children. According to World Health Organization (WHO), estimation of about 1.5 billion episodes of diarrhea with 3 billion mortality occur every year in developing countries. The causative agents include bacteria, virus and parasites. Among bacterial infections ,shigella ,salmonella were the important cause. Since diarrhea. The increased peristaltic movements in diarrhea may lead to poor absorption results in malabsorption, poor cognitive development and academic outcomes. The ultimate aim is to reduce infant and child rate of deaths, control the spread of infectious disease, promote healthy lifestyles for a long disease-free life and help ease the problems of children and adolescents. In siddha system of medicine, Kuzhanthaimaruthuvam is the branch of medicine dealing with the health and medical care of infants, children. Kalichal is one among the Purakarananoigal and is divided inti three types- maanthakalichal, kana kalichal and aamakalichal. Aamakalichal is a commonly occurring disease in infants and children. A detailed search on siddha literatures for the treatment of aamakalichal gives a purley herbal medicine panchadeepakinichooranam in the literature pillaipinimaruthuvam. Though lot of medicines available for Aamakalichal, panchadeeapkinichooranam which is purely herbal, easily available drug and economically low.

MATERIALS AND METHODS

Table:1 Ingredients of PanchadeepakiniChooranam

Collection, Identification and Authentication of the Drug:

The required raw drugs were also purchased from a well reputed country shop. They were authenticated by Botany faculties of Government Siddha Medical College, Palayamkottai.

Purification of the Drug:

All the ingredients of this herbal formulation were purified according to the proper procedure such as air drying and removing dust particlesdescribed in Siddha Classical Literature.

Preparation of the drug:

All this drug individually purified as per the textual reference and then prepared as a fine powder and then mixed together and bottled up in a air tight container.

Biochemical analysis:

Screening the drug Panchadeepakinichooranamto identify the Biochemical properties present in the ingredient.

Chemicals and drugs:

The chemicals used in this study were of analytical grade obtained from Department of Biochemistry, Government Siddha Medical College, Palayamkottai.

Methodology for biochemical analysis:

5 grams of the drug was weighed accurately and placed in a 250ml clean beaker. Then 50ml of distilled water added to it and dissolved well. Then it was boiled well for about 10 minutes. It was cooled and filtered in a 100ml volumetric flask and then it is made upto 100ml with distilled water. This fluid was taken for analysis.

Table2 :Qualitative Analysis of Drug

RESULTS AND DISCUSSION:

The Bio chemical analysis of the trial drug Panchadeepakinichooranamwas tabulated above in table 2.The trial drug Panchadeepakinichooranamcontains,

1. Starch

2. Ferrous Iron

3. Unsaturated compound

4. Amino Acid

5. Calcium

6. Chloride

7. Sulphate

The mode of action of the trial drug Panchadeepakinichooranamwhich brings about the pigmentation of skin in body, may be due to the presence of Sulphate, starch, Ferrous Iron ,Unsaturated compound, Amino Acid, calcium, chloride in it. The study of calcium in diarrheal disorders suggest that Calcium stool losses should be routinely replaced as is currently done for sodium, chloride, potassium, carbonate, and zinc and calcium has the effect of reducing diarrhea.

Conclusion:

Panchadeepakinichooranam is a Siddha Drug taken from a Siddha literature used in the treatment of AamakalichalThe drug is screened for its bio chemical properties. Further, comprehensive pharmacological studies are needed to evaluate its potency and the drug has its own potency to undergo further research.

ACKNOWLEDGEMENT

The author wish to acknowledge our heartythanks to Department of Biochemistry, Government Siddha Medical College, Palayamkottai for their supports to carryout the research works.

References:

Acharya YT, CharakaSamhita of Agnivesha, VimanaSthana, 2^nd Ed, Vol.2,. Reprint edition., Published by ChaukhambaOrientalia; Varanasi:, 2015. p. 262.

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