Abstract

Background : The Thirijathadhi Mathirai is a herbal combination of medicine used for Asthma, Hypertension, Cough, Wheezing, Dyspepsia, Vomiting, Giddiness, Hic-cup, Madness, mania, Pulmonary tuberculosis. Sore throat, Spleen disorder, Rheumatism, Heart disease. Thirst, Fever, Prickling pain in abdomen. Objectives: To characterize the herbal drug “ Thirijathadhi Mathirai” Materials and Methods: The ingredients such as Lavangapattai, lavanga pathiri, Elakkai, Thippili, Karkandu, Thiratchai, Athimathuram  karchoorakai, honey. The drugs were prepared as per Siddha literature “ Anubava Vaithiya Deva Ragasiyam”. The drugs were analysed by using FTIR spectrum Result: FTIR Characterization shows the presence of some functional group such as carboxylic acid, Carbondioxide, imine / oxime. alkyl aryl ether, anhydride, alkenes, Halo compounds, alkyl halides, 1,2,3 trisubstituted. Where identified in Siddha herbal formulation. “ Thirijathadhi  Mathirai”.  This study forms the base for the pharmaceutical analysis of Thirijathadhi mathirai which will be followed by safety and efficacy studies later. Conclusion: The instrumental analysis FTIR study for Thirijathadhi Mathirai shows the presence of functional groups through the stretch and bends which responsible for its functional activity.  It was to subject for further many studies to validate its efficacy and safety through proper standardization procedure.  For its potency.